Top 50 NGOs Leveraging AI to Drive Social Impact and Address Global Challenges

Introduction

The non-profit sector is experiencing a significant transformation fueled by advancements in artificial intelligence (AI). As global challenges become more complex, NGOs are increasingly turning to AI to enhance their operations, improve efficiency, and amplify their impact. From humanitarian aid to environmental conservation, AI is helping these organizations analyze vast datasets, predict trends, and implement more effective solutions.

Leading NGOs are embracing AI to tackle pressing issues such as poverty, education, health, and climate change. By integrating AI into their strategies, these organizations are not only increasing their reach but also developing innovative approaches to solve problems that traditional methods cannot adequately address. This blog post highlights 50 prominent NGOs that are pioneering AI-driven solutions to make a substantial difference in the world.

The Importance of AI in the NGO Sector

AI’s impact on the NGO sector extends beyond operational improvements; it is revolutionizing how these organizations address global challenges by:

As these organizations continue to adopt AI technologies, they are setting new standards for social innovation, making their missions more achievable and impactful.

Criteria for Leading NGOs Utilizing AI

The most influential NGOs leveraging AI excel in several key areas:

By focusing on these areas, NGOs are not only advancing their missions but also contributing to the broader discourse on ethical and impactful AI use.

50 Top NGOs Leveraging AI for Social Impact in 2025

This list features 50 standout NGOs that are at the forefront of using AI to drive social impact and tackle global challenges. From health and education to climate change and humanitarian aid, these organizations are pioneering innovative solutions that leverage AI’s power to create a better world.

While not ranked, this diverse compilation showcases the range of ways in which AI is being harnessed to improve lives and foster sustainable development globally.

1. International Rescue Committee (IRC) 

The International Rescue Committee (IRC), based in New York City, supports individuals affected by conflict and disaster, helping them rebuild their lives with dignity. Through innovative use of AI, the IRC enhances its humanitarian efforts, notably with “aprendIA,” an AI-driven educational chatbot that delivers personalized learning experiences to children in crisis-affected areas, improving educational outcomes where traditional schooling is disrupted.

Additionally, the IRC’s “Signpost” initiative leverages AI to provide critical information to displaced populations, offering access to essential resources through digital channels, help centers, and social media. By employing AI in early-warning systems for climate resilience, the IRC anticipates severe events like floods, enabling timely cash assistance and effective community preparation.

2. Opportunity International

Opportunity International, a Chicago-based nonprofit, is committed to breaking the cycle of poverty by empowering individuals with financial resources, training, and support. Through microloans, savings accounts, and business training, the organization enables entrepreneurs, particularly women, to grow businesses, create jobs, and improve their communities. Their mission also includes enhancing education and healthcare access, fostering sustainable development in underserved regions.

In Malawi, Opportunity International has launched “UlangiziAI,” an AI-powered multilingual chatbot that provides farmers with instant agricultural advice via WhatsApp. UlangiziAI addresses queries in English and Chichewa, saving farmers in remote areas days of travel. During its pilot, the chatbot handled over 4,000 queries and earned high praise from users. Plans are underway to expand this innovation to Kenya, alongside the organization’s broader efforts to implement AI tools in education, exemplifying its commitment to localized, technology-driven solutions for sustainable development.

3. Zero Emissions World (ZEW)

Zero Emissions World (ZEW), based in Portugal, is dedicated to combating climate change by empowering individuals and organizations to actively participate in environmental conservation efforts. Their mission focuses on fostering a global community committed to reducing emissions and promoting sustainable practices. Through a gamified platform, ZEW presents social and environmental projects as engaging ‘missions,’ encouraging users to contribute to positive change worldwide. 

Leveraging artificial intelligence, ZEW enhances donor engagement by analyzing data to provide personalized mission recommendations aligned with individual motivations and preferences. This AI-driven approach not only streamlines the donation process but also fosters sustained involvement in environmental and social initiatives. By integrating AI capabilities, ZEW aims to create a more impactful and transparent platform for global climate action.

4. Animal Ethics

Animal Ethics, based in Portugal, is a nonprofit organization dedicated to promoting respect for nonhuman animals through outreach, research, and education. Their mission focuses on fostering a global community that acknowledges the moral consideration of all sentient beings. They support and research interventions to improve the lives of animals in the wild, such as vaccinations and assistance during natural disasters. Additionally, they explore how future technologies can help wild animals on a large scale, aiming to mitigate catastrophic risks and enhance conservation efforts. 

In their commitment to advancing animal welfare, Animal Ethics has developed “Senti,” an AI-powered assistant designed to provide information and answer questions related to animal ethics and wild animal welfare. This initiative leverages artificial intelligence to disseminate knowledge and engage the public in discussions about ethical considerations concerning animals. 

5. Afri-SET

Afri-SET, based in West Africa, is dedicated to enhancing air quality monitoring by evaluating and calibrating low-cost sensors, thereby empowering communities to make informed decisions about air quality. Their mission focuses on providing accessible knowledge about the performance of these sensors in the African context, aiming to improve air quality monitoring across the region. 

Leveraging artificial intelligence, Afri-SET has developed a smart database capable of handling data from various sensors, regardless of their manufacturer. This AI-powered solution streamlines the processing of raw sensor data, converting it into a unified format and identifying pollution hotspots. By democratizing access to critical air quality information, Afri-SET facilitates scalable and impactful air quality monitoring across Africa.

6. Data Scientists Network (Nigeria)

Data Science Nigeria (DSN), is a leading AI and Data Science organization based in Nigeria. Established in 2016, DSN is committed to nurturing 1 million AI talents and developing AI solutions to enhance the lives of 2 billion people in emerging markets. Their mission focuses on building a world-class AI knowledge, research, and innovation ecosystem that delivers high-impact transformational research, business applications, AI-first start-ups, and social good use cases. 

Leveraging artificial intelligence, DSN has developed various platforms and initiatives to advance AI education and application. These include AI bootcamps, summer schools for students, AI+ knowledge platforms, and AI clubs in secondary schools and universities. Additionally, DSN conducts research and publishes white papers to promote the use of data science and AI in addressing business and socioeconomic development issues in emerging markets. 

7. PATH

PATH, based in Seattle, Washington, is a global health nonprofit organization dedicated to advancing health equity by accelerating innovation in health technologies and solutions. Their mission focuses on improving health systems, developing vaccines and medicines, and enhancing diagnostics to ensure that health solutions are accessible and affordable for all. 

Leveraging artificial intelligence, PATH enhances its health initiatives by developing AI models that optimize the analysis of health data, supporting clinical decision-making, and accelerating drug development. The organization has appointed a Chief AI Officer to integrate AI effectively and ethically into their health solutions, aiming to transform healthcare delivery and improve patient outcomes. 

8. Amref Health Africa

Amref Health Africa, based in Nairobi, Kenya, is the largest Africa-based healthcare nonprofit organization, committed to improving health systems across the continent by training health workers and providing essential services in underserved areas. Their mission focuses on building sustainable health solutions and addressing critical health challenges such as maternal and child health, HIV, and infectious diseases.

Leveraging artificial intelligence, Amref Health Africa has developed AI-powered tools to address malnutrition in Kenya. In collaboration with Microsoft’s AI for Good initiative, the organization has created predictive models to identify at-risk populations, enabling targeted interventions that improve nutrition outcomes. This AI-driven approach is revolutionizing health service delivery, ensuring timely responses to public health challenges.

9. Rainforest Connection

Rainforest Connection, headquartered in San Francisco, California, is a nonprofit organization dedicated to protecting rainforests by leveraging advanced technologies. Their mission focuses on enabling on-the-ground partners to safeguard rainforests through real-time monitoring and rapid response to threats such as illegal logging and poaching. By utilizing eco-acoustic technology, they provide critical data to preserve these vital ecosystems. 

Central to their approach is the Guardian Platform, which employs artificial intelligence and machine learning to analyze continuous audio data captured by solar-powered devices. These devices, often constructed from upcycled smartphones, monitor ambient sounds within rainforests, detecting chainsaws, trucks, and other signs of illegal activity. The AI-driven system processes this data in real-time, sending immediate alerts to local rangers, thereby facilitating prompt interventions to protect biodiversity and prevent deforestation. 

10. UNICEF

UNICEF, headquartered in New York City, USA, is a global organization committed to protecting the rights of children and improving their well-being. Its mission centers on ensuring access to health, education, equality, and protection for every child, particularly those in vulnerable communities. Through its innovative programs, UNICEF addresses critical challenges to create a safer, healthier, and more equitable world for children.

Leveraging artificial intelligence, UNICEF has implemented transformative solutions to enhance its impact. The Generation AI Initiative ensures that AI systems prioritize children’s rights, while its Venture Fund supports startups developing AI-driven tools for education and healthcare, such as AI-powered diagnostics and online learning platforms. Additionally, UNICEF’s policy guidance on AI offers practical recommendations for ethical and inclusive AI systems. These efforts demonstrate UNICEF’s commitment to harnessing AI for the betterment of children’s lives worldwide.

11. One Acre Fund

One Acre Fund, founded in 2006 and headquartered in Kakamega, Kenya, is a nonprofit organization dedicated to empowering smallholder farmers in Sub-Saharan Africa. Its mission is to provide farmers with the tools, financing, and training necessary to increase crop yields and improve livelihoods. Operating in nine countries, One Acre Fund serves over 1.6 million farm families directly and more than 4 million farmers indirectly, focusing on areas such as improved seed and fertilizer access, agricultural training, and market facilitation. 

To enhance its operations, One Acre Fund integrates artificial intelligence (AI) and data analytics into its programs. By leveraging AI-driven data science capabilities, the organization identifies farmers at risk of defaulting on seasonal loans, thereby increasing operational efficiency. Additionally, One Acre Fund employs AI solutions to support decision-making processes, improve service delivery, and promote a data-driven culture within the organization

12. Digital Green

Digital Green, founded in 2008 and headquartered in Washington, D.C., is a global development organization focused on empowering small-scale farmers through technology and partnerships. Operating in countries like India, Ethiopia, and Kenya, Digital Green collaborates with governments and community organizations to enhance agricultural productivity and income levels for farmers.

Digital Green incorporates artificial intelligence (AI) into its services to revolutionize agricultural extension systems. By using AI-powered tools, the organization provides personalized, cost-effective support to farmers, significantly reducing the costs of outreach while boosting farmers’ incomes. This integration of AI helps scale tailored advice, ensuring farmers receive the most relevant information for improving their practices.

13. Ushahidi

Ushahidi, founded in 2008 and headquartered in Nairobi, Kenya, is a nonprofit technology company specializing in developing open-source software for information collection, visualization, and interactive mapping. Its mission is to empower communities by providing tools that democratize data, enabling individuals to collaboratively address pressing challenges. Ushahidi’s platform has been instrumental in various applications, including crisis response, human rights reporting, and election monitoring, facilitating the amplification of citizen voices in over 160 countries.

In its commitment to innovation, Ushahidi is integrating artificial intelligence (AI) to enhance data accessibility and equity. By leveraging AI, the organization aims to improve the efficiency and effectiveness of its platforms, ensuring that data is not only accessible but also secure, thereby empowering communities with greater control and transparency. This strategic direction underscores Ushahidi’s dedication to harnessing advanced technologies to support social impact initiatives globally.

14. Africa’s Voices Foundation (AVF)

Africa’s Voices Foundation (AVF), established in 2014 and headquartered in Nairobi, Kenya, is a nonprofit organization dedicated to amplifying citizen voices to inform and improve public services and development initiatives across Africa. Emerging from research at the University of Cambridge, AVF collaborates with partners such as UNICEF, Oxfam, and the MasterCard Foundation to facilitate inclusive public discussions on governance, health, and education. 

AVF integrates artificial intelligence (AI) to enhance its mission of interpreting social evidence. By employing AI-driven natural language processing and machine learning techniques, AVF analyzes large volumes of citizen-generated data from interactive radio shows, SMS, and social media. This approach enables the organization to extract meaningful insights from diverse public opinions, ensuring that citizen perspectives are central to decision-making processes.

15. Oxfam

Oxfam, headquartered in Nairobi, Kenya, is a global organization dedicated to combating poverty and injustice by addressing the root causes of inequality. Its mission focuses on empowering vulnerable communities, promoting sustainable development, and advocating for human rights. Oxfam operates in numerous countries, implementing programs that provide immediate relief during crises and support long-term development initiatives.

Leveraging artificial intelligence, Oxfam has enhanced its operational efficiency and program effectiveness. By partnering with Ontinue, Oxfam has strengthened its cybersecurity through AI-powered managed extended detection and response (MXDR) services, ensuring the protection of sensitive data and the continuity of its global operations. Additionally, Oxfam’s Innovation Lab explores market-based solutions to development challenges, potentially incorporating AI to analyze data and develop scalable interventions. These AI-driven approaches enable Oxfam to respond more effectively to humanitarian needs and contribute to sustainable development worldwide.

16. Plan International

Plan International, headquartered in Woking, United Kingdom, is a global organization committed to advancing children’s rights and promoting gender equality. Its mission focuses on empowering children, particularly girls, by addressing key issues such as education, health, and protection from violence. Operating in over 75 countries, Plan International works to create lasting positive change in the lives of children and their communities.

Leveraging artificial intelligence, Plan International has integrated AI to enhance its advocacy and operational efficiency. One example is its collaboration with HURIDOCS and Google.org fellows to develop a machine learning-powered human rights database. This tool helps streamline access to crucial data, supporting effective advocacy for girls’ rights on international platforms. Additionally, Plan International Norway partnered with BearingPoint to create an AI-driven application that automates program reporting, reducing manual workload and allowing staff to focus more on impactful program delivery. These AI-driven innovations help Plan International amplify its mission to promote children’s rights and gender equality globally.

17. Care International

CARE International, headquartered in Geneva, Switzerland, is a global humanitarian organization dedicated to combating poverty and social injustice. Their mission focuses on empowering marginalized communities, particularly women and girls, to achieve social and economic equality. In recent years, CARE International has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, CARE International has developed tools to predict and prevent health crises, such as using AI models to forecast and mitigate disease outbreaks. Additionally, CARE International’s Office of Innovation has invested in AI-powered education and health system solutions, supporting startups that utilize AI to improve learning outcomes and healthcare services. Through these initiatives, CARE International aims to harness AI to advance child rights and well-being globally.

18. Doctors Without Borders

Doctors Without Borders (Médecins Sans Frontières, MSF), headquartered in Geneva, Switzerland, is a global humanitarian organization dedicated to providing medical care to populations in crisis. Their mission focuses on delivering emergency medical aid to those affected by conflict, epidemics, disasters, or exclusion from healthcare. In recent years, MSF has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, MSF has developed tools to improve diagnostic accuracy and treatment effectiveness. For instance, they have created a smartphone application, known as ASTapp, which uses image processing and AI technology to assist non-expert microbiologists in interpreting tests that measure antibiotic resistance. This tool aims to guide clinicians in selecting the most appropriate antibiotics, thereby improving patient outcomes.

19. World Wildlife Fund (WWF)

The World Wildlife Fund (WWF), headquartered in Woking, United Kingdom, is a leading global conservation organization committed to protecting the planet’s natural resources and biodiversity. Their mission focuses on conserving the world’s most vulnerable ecosystems and species through science-based initiatives, advocacy, and partnerships. In recent years, WWF has increasingly integrated artificial intelligence (AI) to enhance its conservation efforts.

Leveraging AI, WWF has developed several innovative tools to monitor and protect wildlife and ecosystems. One such initiative is Wildlife Insights, an online platform that uses machine learning to automatically identify and tag animals in camera trap images. This technology enables researchers to process thousands of images within minutes, significantly reducing the time required for data analysis and allowing for more timely conservation interventions.

20. Save the Children

Save the Children, based in London, United Kingdom, is a leading global organization dedicated to improving children’s lives worldwide. Their mission focuses on ensuring that every child has access to healthcare, education, and protection from harm. Save the Children is committed to responding to emergencies and advocating for children’s rights, particularly in areas affected by conflict, disaster, and poverty.

Save the Children is leveraging AI to enhance child protection efforts in Kenya, focusing on addressing critical issues such as child labor, trafficking, and abuse. With Omdena’s collaboration, the organization identified gaps in existing child protection frameworks and developed AI-driven solutions to improve reporting, response services, and resource allocation. Omdena’s expertise in AI facilitated predictive analysis models that informed policy recommendations and tailored interventions, ultimately strengthening the support systems for vulnerable children in Kenya and setting a benchmark for similar global initiatives.

21. World Food Programme (WFP)

The World Food Programme (WFP), headquartered in Rome, Italy, is the leading humanitarian organization addressing global hunger. Their mission focuses on delivering food assistance to those in need, promoting food security, and supporting sustainable development to eradicate hunger worldwide. In recent years, WFP has increasingly integrated artificial intelligence (AI) to enhance its programs and initiatives.

Leveraging AI, WFP has developed several innovative tools to improve its operations. One such initiative is the UN AI Smart Mission Planner, designed to optimize mission planning and travel resources for humanitarians, thereby accelerating emergency response and enhancing resource utilization across the UN network.  Additionally, WFP’s AI Sandbox serves as a vital resource for assessing the feasibility and potential impact of new AI projects before scaling them up, ensuring that only the most promising and responsible AI solutions are implemented.

22. Habitat for Humanity

Habitat for Humanity, based in Atlanta, Georgia, is a global nonprofit organization dedicated to building affordable housing and promoting homeownership. Their mission focuses on empowering families by providing safe, decent, and affordable homes, fostering community stability and self-reliance. In recent years, the organization has integrated artificial intelligence (AI) to enhance both its operations and fundraising strategies.

Using AI, Habitat for Humanity has optimized fundraising campaigns through tools like Arjuna’s ExactAsk, which analyzes donor data to personalize requests and significantly increase average donation sizes. Additionally, Habitat has partnered with RealPage to leverage AI in housing development, improving operational efficiencies and resource allocation, thereby advancing its mission of building affordable, sustainable communities.

23. Greenpeace

Greenpeace, based in Amsterdam, Netherlands, is an independent global campaigning organization focused on environmental protection and peace. Their mission is to protect biodiversity, reduce pollution, and combat climate change through non-violent methods. Greenpeace aims to secure the Earth’s ability to support life in all its forms by advocating for systemic changes that promote environmental sustainability.

Leveraging artificial intelligence, Greenpeace has explored ways to assess and mitigate environmental impacts, including endorsing the Artificial Intelligence Environmental Impacts Act of 2024 to track AI’s energy consumption and emissions. Additionally, Greenpeace has utilized AI-powered tools like Dataro’s Predict to enhance donor engagement and retention, thereby increasing support for its environmental campaigns and initiatives.

24. The International Committee of the Red Cross (ICRC)

The International Committee of the Red Cross (ICRC), headquartered in Geneva, Switzerland, is a humanitarian organization dedicated to protecting and assisting victims of armed conflict and other situations of violence. Their mission focuses on providing impartial aid, promoting respect for international humanitarian law, and preventing human suffering. In recent years, the ICRC has increasingly integrated artificial intelligence (AI) to enhance its operations and address emerging challenges in conflict zones.

Leveraging AI, the ICRC has developed tools to assess and mitigate the impact of new technologies on humanitarian efforts. They have explored the implications of AI in military decision-making, emphasizing the need for human oversight to prevent unintended consequences. Additionally, the ICRC has engaged in discussions about the ethical use of AI in warfare, advocating for international regulations to ensure that AI applications align with humanitarian principles. Through these initiatives, the ICRC aims to harness AI responsibly, ensuring that technological advancements support and enhance humanitarian action.

25. ActionAid

ActionAid, based in Johannesburg, South Africa, is a global federation focused on eradicating poverty and promoting social justice. Their mission is centered around empowering women and girls, advocating for human rights, and fostering sustainable development through community-driven initiatives. ActionAid strives to address the root causes of poverty and injustice by supporting marginalized communities and advancing social equality.

Leveraging artificial intelligence, ActionAid has integrated AI tools to optimize fundraising and engagement. In collaboration with Dataro, ActionAid Australia used machine learning to target potential donors more effectively, resulting in a significant increase in donations. Additionally, ActionAid Italy developed “Aida,” an AI-powered chatbot that provides real-time information about the organization’s initiatives, making it easier for supporters to interact and stay informed.

26. Mercy Corps

Mercy Corps, based in Portland, Oregon, is a global humanitarian organization focused on alleviating poverty and fostering sustainable development. Their mission is to help communities in crisis build better lives by providing support in areas such as food security, economic development, and climate resilience. Mercy Corps aims to address the root causes of poverty and conflict through innovative and impactful solutions.

Leveraging artificial intelligence, Mercy Corps has implemented AI-driven initiatives like the “AI for Climate Resilience” program, which focuses on improving climate resilience in vulnerable regions through advanced weather forecasting and early warning systems. Additionally, in partnership with Cloudera, they have developed AI tools to optimize humanitarian aid delivery, enabling field teams to make data-driven decisions and improve crisis response efforts.

27. Human Rights Watch

Human Rights Watch, based in New York City, is an international organization focused on investigating and advocating for human rights globally. Their mission is to defend the rights of people worldwide by exposing human rights abuses and pushing governments and other powerful entities to respect human dignity and justice. HRW works to hold perpetrators accountable and ensure justice for victims through rigorous research and advocacy efforts.

Human Rights Watch has engaged with artificial intelligence to assess its potential impact on human rights. The organization has raised concerns about AI technologies perpetuating biases and discrimination, particularly in areas such as hiring practices and surveillance. HRW calls for strong regulatory frameworks to ensure AI development aligns with human rights principles, advocating for policies that prevent AI tools from infringing on civil liberties and disproportionately affecting marginalized communities.

28. WaterAid

WaterAid, based in London, United Kingdom, is an international organization dedicated to improving access to safe water, sanitation, and hygiene in the world’s poorest communities. Their mission is to transform lives by enabling communities to access clean water and sanitation, empowering them to break the cycle of poverty. WaterAid works with local partners to implement sustainable projects that meet the real needs of communities and improve public health.

Leveraging artificial intelligence, WaterAid has integrated AI and automation to enhance its operational efficiency. By using AI to identify potential risks and automate routine tasks, the organization has optimized its internal processes. Additionally, WaterAid has employed AI-enabled models to deliver personalized micro-trainings to staff, which has led to measurable behavior change and increased effectiveness in their mission to provide clean water and sanitation to those in need.

29. Heifer International

Heifer International, based in Little Rock, Arkansas, is a global nonprofit organization dedicated to ending hunger and poverty. Their mission focuses on empowering smallholder farmers through sustainable agricultural solutions, economic development, and environmental stewardship. Heifer works closely with communities to implement programs that improve food security, increase incomes, and enhance resilience to climate change.

Leveraging artificial intelligence, Heifer has collaborated with FruitPunch AI to launch the AI for Women Farmers Challenge. This initiative helps rural women farmers in Nepal use AI tools to digitize business records, access markets, and secure financing. Additionally, Heifer has partnered with IBM to use AI and blockchain technologies in Honduras, assisting coffee and cocoa farmers with supply chain transparency and data-driven decision-making to promote sustainable farming practices.

30. SOS Children’s Villages

SOS Children’s Villages, based in Innsbruck, Austria, is a global nonprofit organization focused on providing family-like care to children who have lost parental care or are at risk of losing it. Their mission centers on creating stable and nurturing environments for children, supporting their overall well-being, and helping them grow into self-reliant adults. The organization operates in over 130 countries, providing family-based care, education, and health services to vulnerable children.

Leveraging artificial intelligence, SOS Children’s Villages has implemented AI-driven tools like Rafiki, a digital care assistant. This chatbot helps caregivers by providing real-time information and support on child protection, mental health, and parenting. Currently available in several African countries, Rafiki is expanding its reach, demonstrating how technology can enhance the organization’s efforts to improve care for children and families in need.

31. GlobalGiving

GlobalGiving, based in Washington, D.C., connects donors with grassroots projects around the world. Their mission is to empower local organizations by providing resources and support to address community needs. Through their platform, GlobalGiving has facilitated millions in donations to thousands of projects, improving lives in over 175 countries.

To enhance their operations, GlobalGiving has incorporated artificial intelligence to improve project assessment, optimize resource allocation, and boost donor engagement. By utilizing AI-driven analytics, the organization can ensure that funds are allocated efficiently, maximizing the impact of their efforts to support local initiatives and foster sustainable development.

32. Feeding America

Feeding America, headquartered in Chicago, Illinois, is the largest hunger-relief organization in the United States. Their mission focuses on ending hunger by providing food to people in need through a network of over 200 food banks and 60,000 food pantries and meal programs across the country. In 2020, Feeding America distributed over 6 billion meals to individuals facing hunger. 

In recent years, Feeding America has increasingly integrated artificial intelligence (AI) to enhance its operations and support its mission. They have utilized AI-driven analytics to optimize food distribution, predict demand, and reduce food waste. By leveraging AI, Feeding America aims to improve efficiency, ensure that food reaches those in need, and contribute to the broader goal of ending hunger in the United States.

33. Ashoka

Ashoka, founded in 1980 by Bill Drayton, is a global nonprofit organization headquartered in Arlington, Virginia. It is the world’s largest network of social entrepreneurs, with over 3,800 Ashoka Fellows in more than 90 countries. These individuals are recognized for their innovative solutions to social problems and their potential for systemic change. Ashoka provides financial support, professional partnerships, and a platform for these changemakers to collaborate and scale their impact. 

In recent years, Ashoka has increasingly integrated artificial intelligence (AI) to enhance its operations and support its mission. The organization has utilized AI-driven analytics to identify emerging social trends, assess the effectiveness of various initiatives, and optimize resource allocation. By leveraging AI, Ashoka aims to improve its ability to support social entrepreneurs and accelerate the adoption of innovative solutions to pressing global challenges.

34. Friends of the Earth

Friends of the Earth, founded in 1969 and based in the United Kingdom, is an international environmental network with member groups in over 70 countries. Their mission is to promote environmental justice, protect biodiversity, and address climate change and pollution. Through grassroots activism and advocacy, they empower communities to take action for a sustainable and just future.

While the organization acknowledges the potential of artificial intelligence (AI) for positive environmental impact, it has also raised concerns about its risks. Friends of the Earth has highlighted the potential for AI to exacerbate climate disinformation and increase energy consumption, contributing to carbon emissions. However, they are exploring how AI can be responsibly used to support their environmental campaigns, ensuring that technology aligns with their mission of protecting the planet.

35. BRAC

BRAC, a leading international development organization based in Bangladesh, is leveraging artificial intelligence (AI) to enhance its development programs, particularly in education and healthcare. The organization has explored AI’s potential in delivering remote learning solutions, especially during the COVID-19 pandemic, by adapting its education delivery through mobile phones, radio, and television broadcasts in countries like Bangladesh, Tanzania, and Uganda. BRAC is also developing machine learning-based systems to improve healthcare, such as a pregnancy risk categorization system aimed at improving maternal health outcomes by targeting resources for women at higher risk of complications.

Additionally, BRAC’s Social Innovation Lab has been hosting dialogues focused on AI’s application in the development sector, discussing how to localize AI solutions to address challenges in the Global South. With a focus on both technological integration and community impact, BRAC continues to demonstrate its commitment to using AI to improve educational access and healthcare services, ensuring the relevance and adaptability of its initiatives to the communities it serves.

36. Kiva

Kiva, a global nonprofit organization dedicated to expanding financial access for underserved communities, has been actively integrating artificial intelligence (AI) to enhance its services. In September 2024, Kiva partnered with OpenAI to develop a Resource Hub aimed at assisting small businesses and social enterprises in leveraging AI tools like ChatGPT for content creation, marketing, and other operational tasks. This collaboration provides easy-to-follow guidance, enabling entrepreneurs to utilize AI effectively, thereby improving efficiency and fostering growth. 

Additionally, Kiva has been involved in AI-related initiatives through Kiva AI, a platform focused on delivering high-quality data labeling, annotation, and reinforcement learning from human feedback (RLHF) solutions. Kiva AI aims to enhance AI model development by providing scalable and cost-effective human feedback, ensuring that AI applications are trained with accurate and contextually relevant data. This approach addresses the critical need for quality human input in AI development, contributing to more effective and reliable AI systems.

37. Malaria Consortium

Malaria Consortium, an international nonprofit focused on combating malaria and other communicable diseases, is utilizing artificial intelligence (AI) to enhance its healthcare initiatives. In 2020, the organization conducted a pilot study using AI on mobile devices to accurately determine respiratory rates in children under five in low-resource settings. This approach aims to improve the diagnosis of pneumonia, a leading cause of child mortality, by making healthcare tools more accessible and efficient in remote areas.

Furthermore, Malaria Consortium is exploring AI applications to strengthen health systems and improve decision-making processes through data. By integrating digital health strategies, including AI, the organization is working to enhance data access and quality, ultimately improving healthcare delivery and outcomes in the communities it serves.

38. Global Citizen

Global Citizen, an international advocacy organization focused on ending extreme poverty, is exploring the role of artificial intelligence (AI) in shaping global governance and promoting social justice. The organization has actively engaged with AI through reports such as “Global Citizen Deliberation on Artificial Intelligence,” which emphasizes the need for citizen involvement in AI governance. The report calls for global deliberations to ensure AI advancements align with societal values and contribute positively to addressing poverty and inequality.

Additionally, Global Citizen is advocating for responsible AI development to protect human rights and freedoms. The organization is exploring the implications of AI on civic space and civil rights, stressing the importance of ethical considerations in AI applications. Through these initiatives, Global Citizen integrates AI discussions into its broader advocacy work, aiming to influence AI governance and ensure that technological progress aligns with its mission of promoting social justice and global equity.

39. UNHCR

The United Nations High Commissioner for Refugees (UNHCR), based in Geneva, Switzerland, is committed to protecting the rights and well-being of refugees and displaced populations worldwide. By providing access to safety, education, healthcare, and livelihood opportunities, UNHCR fosters resilience and empowers communities to rebuild their lives with dignity and hope.

UNHCR leverages AI to enhance its humanitarian impact. In Somalia, “Project Jetson” uses predictive analytics to forecast displacement patterns, enabling proactive resource allocation and crisis management. The organization also applies generative AI to analyze unstructured feedback from refugee communities, identifying emerging trends and needs for data-driven interventions. Furthermore, AI-driven tools support operational efficiency, such as streamlining refugee registration and facilitating faster access to essential services. These innovations allow UNHCR to adapt to evolving challenges and deliver timely, targeted support to vulnerable populations.

40. World Resources Institute

The World Resources Institute (WRI), headquartered in Washington, D.C., is dedicated to advancing environmental sustainability, economic opportunity, and human well-being. Through research and partnerships, WRI tackles critical global issues like climate change, deforestation, and sustainable urban development, ensuring a healthier planet for current and future generations.

WRI integrates AI into its environmental efforts to drive impactful solutions. Its Global Forest Watch platform uses satellite technology and AI to provide near-real-time monitoring of forests, helping prevent deforestation and support conservation strategies. Additionally, WRI’s Data Lab applies AI to analyze complex datasets, offering insights that guide sustainable development initiatives and climate resilience strategies worldwide.

41. International Medical Corps

International Medical Corps, based in Los Angeles, California, is a global humanitarian organization that provides healthcare and emergency relief to communities affected by conflict, disaster, and disease. Their mission focuses on strengthening local healthcare systems and training healthcare workers to provide sustainable medical services, while also addressing the root causes of health disparities in vulnerable regions.

The organization integrates artificial intelligence (AI) to enhance its response and operational capabilities. Using IBM’s analytics platform, International Medical Corps accelerates reporting and decision-making, which allows for quicker deployment of medical resources and responders during emergencies. Additionally, AI-driven tools are employed to streamline healthcare data collection and analysis, enabling better-targeted interventions and more efficient healthcare delivery in crisis situations.

42. The Nature Conservancy

The Nature Conservancy (TNC), based in Arlington, Virginia, is dedicated to conserving the lands and waters on which all life depends. Through their global efforts, TNC focuses on protecting nature for its intrinsic value and its critical role in supporting human life, ensuring clean air, water, and sustainable ecosystems for future generations.

TNC integrates artificial intelligence (AI) to advance its conservation initiatives. In Palmyra Atoll, AI-powered image analysis helped identify two additional seabird species, enhancing habitat restoration efforts. TNC also collaborates with Microsoft to leverage AI for addressing key environmental challenges, such as improving coastal resilience, floodplain management, and watershed protection. Furthermore, AI tools are used to analyze complex natural systems, supporting more sustainable energy planning for hydropower and river protection.

43. IREX

IREX, established in 1968 and headquartered in Washington, D.C., is a global nonprofit organization committed to building a more just, prosperous, and inclusive world by empowering youth, cultivating leaders, strengthening institutions, and extending access to quality education and information. Operating in over 100 countries, IREX collaborates with partners to develop innovative programs that promote positive change and sustainable development.

IREX is leveraging AI in many ways to promote democratic resilience and counter misinformation. One notable example is their project in the Dominican Republic, where they collaborated with Omdena to develop an AI-powered system that detects and analyzes misleading electoral information, particularly targeting youth. This system uses real-time data processing and tailored algorithms to identify misinformation campaigns, helping journalists, civil society organizations, and electoral authorities to monitor and respond effectively. By enhancing the integrity of the electoral process, this initiative serves as a model for using AI to protect democracy from the threats of misinformation globally.

45. Grameen Foundation 

Grameen Foundation, established in 1997 by Alex Counts, is a global nonprofit organization headquartered in Washington, D.C. Inspired by the work of Nobel Laureate Muhammad Yunus, the foundation’s mission is to enable the poor, especially women, to create a world without poverty and hunger. Operating across Asia, Africa, and the Americas, Grameen Foundation empowers marginalized populations through innovative solutions to address the multifaceted challenges of poverty.

In recent years, Grameen Foundation has integrated artificial intelligence (AI) to enhance financial inclusion and decision-making among low-income populations. Collaborating with Accenture Labs, they developed AI-driven applications like Emotional Analytics for Social Enterprises (EASE) and Grameen Guru, which provide real-time insights and financial literacy support. These AI initiatives aim to improve the adoption of financial services, particularly in regions like India, thus promoting financial empowerment globally.

46. Environmental Defense Fund 

Environmental Defense Fund (EDF), established in 1967, is a global nonprofit organization headquartered in New York City. EDF is dedicated to building a vital Earth for everyone, focusing on stabilizing the climate, ensuring sustainable fisheries, and protecting public health through science-based solutions and partnerships.

In recent years, EDF has increasingly integrated artificial intelligence (AI) into its initiatives to enhance environmental protection efforts. Notably, EDF has used AI-driven analytics for hyperlocal air quality mapping in cities like Oakland and London, providing precise data to target pollution hotspots. Additionally, the Smart Boat Initiative uses AI and sensor technologies to transform fishing practices, promoting sustainability. Through these AI applications, EDF aims to develop innovative, data-driven solutions to complex environmental challenges, furthering its mission to create a sustainable future.

47. ACLU

The American Civil Liberties Union (ACLU), founded in 1920, is a nonprofit organization headquartered in New York City. Its mission is to defend and preserve the individual rights and liberties guaranteed to every person in the United States by the Constitution and laws. The ACLU operates nationwide, focusing on areas like free speech, privacy, and equality through litigation, advocacy, and public education.

In recent years, the ACLU has addressed the impact of artificial intelligence (AI) on civil liberties, particularly in perpetuating systemic biases in employment, housing, and credit. The organization advocates for equitable AI systems, challenging discriminatory practices, and policies. It also monitors AI use in national security and law enforcement, warning against potential risks to privacy and freedom. Through these efforts, the ACLU ensures that AI advancements align with constitutional rights and civil liberties.

48. Amnesty International

Amnesty International, founded in 1961 by Peter Benenson, is a global human rights organization headquartered in London, United Kingdom. Its mission is to conduct research and take action to prevent and end grave abuses of human rights worldwide. Operating in over 150 countries, Amnesty International addresses issues such as freedom of expression, abolition of the death penalty, and the rights of refugees and migrants.

Amnesty International has been actively addressing the human rights implications of artificial intelligence (AI) and related technologies. The organization has raised concerns about AI’s role in mass surveillance, discrimination, and the erosion of privacy rights. For example, it has criticized AI-powered welfare systems that may lead to surveillance and discrimination against marginalized groups. Additionally, Amnesty has highlighted the use of AI at borders, emphasizing how such technologies can increase inequalities and undermine the human rights of migrants. Through research and advocacy, Amnesty International seeks to ensure that AI technologies are developed and deployed in ways that respect and uphold human rights globally.

49. Room to Read

Room to Read, founded in 2000 and headquartered in San Francisco, California, is a nonprofit organization dedicated to eliminating illiteracy and gender inequality. Its mission focuses on improving literacy and supporting girls’ education across more than 24 countries. The organization collaborates with local communities to develop essential literacy skills and empower girls to succeed in school and beyond.

While Room to Read has not yet publicly integrated artificial intelligence (AI) into its programs, it continues to explore innovative solutions to enhance education. With a focus on educational access and quality, AI could potentially play a significant role in providing personalized learning experiences, improving literacy tools, and expanding access to resources, all of which could support Room to Read’s mission of transforming education for children globally.

50. GAIN 

The Global Alliance for Improved Nutrition (GAIN), established in 2002 and headquartered in Geneva, Switzerland, is a nonprofit organization dedicated to combating malnutrition worldwide. Its mission is to advance nutrition outcomes by improving the consumption of nutritious and safe food for all people, especially the most vulnerable to malnutrition. Operating in over 25 countries, GAIN collaborates with governments, businesses, and civil society to design and implement food-based policies and programs that encourage the consumption of nutritious and safe foods. 

GAIN has recognized the potential of artificial intelligence (AI) to enhance nutrition programming. The organization has issued a request for proposals to develop AI recommendations aimed at strengthening nutrition initiatives. This initiative seeks to leverage AI technologies to improve the effectiveness and reach of nutrition interventions, aligning with GAIN’s commitment to innovative solutions in the fight against malnutrition. 

51. Operation Smile

Operation Smile, established in 1982 and headquartered in Virginia Beach, Virginia, is a nonprofit organization dedicated to providing free reconstructive facial surgeries to children and adults worldwide who suffer from cleft lips and palates. Their mission is to improve the health and lives of these individuals by offering comprehensive care, including surgeries, dental care, speech therapy, and psychological support. Operating in over 35 countries, Operation Smile has performed more than 400,000 surgeries, transforming the lives of countless patients and their families.

In collaboration with Microsoft, Operation Smile has integrated artificial intelligence (AI) into their operations to enhance patient care and surgical outcomes. By leveraging AI, the organization analyzes pre- and post-surgical photographs to objectively assess the severity of cleft conditions and evaluate surgical results. This integration allows for consistent, measurable evaluations, ensuring high-quality care even in regions with limited access to specialized cleft surgeons. The AI program also aids in educating surgeons in remote areas, bringing the expertise of experienced professionals to underserved communities.

52. mySociety

mySociety, founded in 2003 and headquartered in the United Kingdom, is a nonprofit organization dedicated to empowering citizens through digital technology, research, and data. Its mission is to enhance civic participation by providing tools that enable individuals to engage more effectively with democratic processes. mySociety operates services such as TheyWorkForYou, WhatDoTheyKnow, WriteToThem, and FixMyStreet, which facilitate access to governmental information and promote community involvement. 

In recent years, mySociety has been exploring the integration of artificial intelligence (AI) into its platforms to better serve its mission. The organization has developed an AI framework to guide the ethical and effective use of AI technologies in enhancing civic engagement. This framework addresses considerations for deploying generative AI and machine learning within mySociety’s services, ensuring that technological advancements align with their commitment to responsible and impactful civic tech solutions. 

NGOs and AI: Pioneering Social Impact and Global Change

At the forefront of tackling the world’s most pressing challenges, NGOs are harnessing AI to reshape how social issues are addressed. By embracing cutting-edge technologies and focusing on data-driven, scalable solutions, these organizations are not only enhancing their impact but also driving innovation in the non-profit sector.

Through AI-powered analytics, predictive models, and automated systems, these NGOs are setting new standards by achieving key objectives:

• Enhancing Efficiency: Streamlining operations to allocate resources more effectively and reach more people in need.
• Driving Innovation: Utilizing AI to develop new methods for solving complex global issues like poverty, health crises, and climate change.
• Personalizing Interventions: Tailoring programs to better meet the unique needs of different communities, ensuring more targeted and effective outcomes.

At Omdena, we collaborate with leading NGOs to leverage AI for social good, helping them scale their efforts and maximize their impact. Join us in driving a future where technology empowers organizations to create sustainable, meaningful change.